Search
Descriptor English: Fas-Associated Death Domain Protein
Descriptor Spanish: Proteína de Dominio de Muerte Asociada a Fas
Descriptor proteína del dominio de muerte asociada a fas
Scope note: Proteína adaptadora transductora de señales que se asocia con complejos del RECEPTOR DE TNF. Contiene un dominicio de muerte efector que puede interactuar con dominios de muerte efectores que se encuentran en las CASPASAS INICIADORAS tales como CASPASA 8 y CASPASA 10. La activación de CASPASAS por medio de la interacción con esta proteína desempeña un papel en la cascada de señalización que lleva a la APOPTOSIS.
Descriptor Portuguese: Proteína de Domínio de Morte Associada a Fas
Descriptor French: Protéine à domaine de mort associée à Fas
Entry term(s): FADD Protein, Fas Associating
FADD Protein, Fas-Associating
FADD, Fas-Associating Protein
Fas Associated Death Domain Protein
Fas Associating Protein FADD
Fas Associating Protein with Death Domain
Fas-Associating FADD Protein
Fas-Associating Protein FADD
Fas-Associating Protein with Death Domain
MORT1 Protein
Tree number(s): D12.644.360.024.285.200
D12.644.360.024.500.124
D12.644.360.075.421.200
D12.776.157.057.018.200
D12.776.157.057.500.124
D12.776.476.024.320.550
D12.776.476.024.500.124
D12.776.476.075.421.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053200
Scope note: A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; FAS-ASSOCIATED DEATH DOMAIN PROTEIN was indexed under ADAPTOR PROTEINS, SIGNAL TRANSDUCING 2005 & under CARRIER PROTEINS 1995-2004
History Note: 2007(1995)
DeCS ID: 52311
Unique ID: D053200
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
Fas-Associated Death Domain Protein - Preferred
Concept UI M0245371
Scope note A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS.
Preferred term Fas-Associated Death Domain Protein
Entry term(s) FADD Protein, Fas Associating
FADD Protein, Fas-Associating
FADD, Fas-Associating Protein
Fas Associated Death Domain Protein
Fas Associating Protein FADD
Fas Associating Protein with Death Domain
Fas-Associating FADD Protein
Fas-Associating Protein FADD
Fas-Associating Protein with Death Domain
MORT1 Protein



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey